PREY

MAGI2

ACVRIP1, AIP-1, AIP1, ARIP1, MAGI-2, SSCAM
membrane associated guanylate kinase, WW and PDZ domain containing 2

External Database Linkouts

VEGA | HGNC | OMIM | Entrez Gene | RefSeq | UniprotKB | Ensembl | HPRD
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Novel factors in regulation of activin signaling.

Tsuchida K, Nakatani M, Matsuzaki T, Yamakawa N, Liu Z, Bao Y, Arai KY, Murakami T, Takehara Y, Kurisaki A, Sugino H

Activin type II receptors (ActRIIs) are the primary receptors that transmit the activin signal to intracellular signaling pathways. Binding of activins to ActRIIs recruits the activin type I receptor and initiates downstream signaling. We have found that PDZ proteins, named activin receptor-interacting proteins (ARIPs), specifically associate with ActRIIs. We have studied the mechanism that ARIPs regulate cell surface expression and ... [more]

Mol. Cell. Endocrinol. Oct. 15, 2004; 225(1);1-8 [Pubmed: 15451561]

Throughput

  • Low Throughput

Curated By

  • BioGRID