CHRNB2
Gene Ontology Biological Process
- B cell activation [ISS]
- associative learning [ISS]
- behavioral response to nicotine [IMP]
- calcium ion transport [ISS]
- cation transmembrane transport [IDA, TAS]
- central nervous system projection neuron axonogenesis [ISS]
- cognition [IMP]
- ion transmembrane transport [TAS]
- ion transport [NAS]
- lateral geniculate nucleus development [ISS]
- learning [IMP]
- locomotory behavior [ISS]
- membrane depolarization [ISS]
- memory [IMP]
- negative regulation of action potential [ISS]
- neurological system process [IMP]
- optic nerve morphogenesis [ISS]
- positive regulation of B cell proliferation [ISS]
- positive regulation of dopamine secretion [ISS]
- regulation of circadian sleep/wake cycle, REM sleep [ISS]
- regulation of dendrite morphogenesis [ISS]
- regulation of dopamine metabolic process [ISS]
- regulation of dopamine secretion [ISS]
- regulation of synapse assembly [ISS]
- regulation of synaptic transmission, dopaminergic [ISS]
- response to cocaine [ISS]
- response to ethanol [ISS]
- response to hypoxia [IDA]
- response to nicotine [IDA]
- sensory perception of pain [ISS]
- sensory perception of sound [ISS]
- signal transduction [IDA]
- smooth muscle contraction [ISS]
- social behavior [ISS]
- synaptic transmission [TAS]
- synaptic transmission involved in micturition [ISS]
- synaptic transmission, cholinergic [ISS]
- vestibulocochlear nerve development [ISS]
- visual learning [IMP]
- visual perception [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
LMF1
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.754349869 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.754349868581877, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CHRNB2 LMF1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9615 | BioGRID | 3113589 |
Curated By
- BioGRID