RAMP2
Gene Ontology Biological Process
- adherens junction assembly [IDA]
- angiogenesis [IDA]
- basement membrane assembly [ISS]
- cAMP biosynthetic process [IDA]
- calcium ion transport [IDA]
- cellular response to vascular endothelial growth factor stimulus [ISS]
- heart development [ISS]
- negative regulation of endothelial cell apoptotic process [IDA]
- negative regulation of vascular permeability [IDA]
- positive regulation of angiogenesis [ISS]
- positive regulation of cAMP biosynthetic process [IDA]
- positive regulation of gene expression [IDA]
- protein localization to plasma membrane [IDA]
- protein transport [IDA]
- receptor internalization [IDA]
- regulation of blood pressure [ISS]
- sprouting angiogenesis [ISS]
- tight junction assembly [IDA]
- vascular smooth muscle cell development [ISS]
- vasculogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GDAP1
Gene Ontology Biological Process
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.874767731 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.874767730674007, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RAMP2 GDAP1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8953 | BioGRID | 3064359 |
Curated By
- BioGRID