BAIT
UGT1A8
UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H
UDP glucuronosyltransferase 1 family, polypeptide A8
GO Process (16)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- cellular glucuronidation [IDA]
- cellular response to hormone stimulus [IBA]
- coumarin metabolic process [IC]
- drug metabolic process [IDA]
- fatty acid metabolic process [IC, IDA]
- flavone metabolic process [IDA]
- flavonoid biosynthetic process [IBA]
- flavonoid glucuronidation [IDA]
- negative regulation of catalytic activity [IDA]
- negative regulation of cellular glucuronidation [IDA]
- negative regulation of fatty acid metabolic process [IC, IDA]
- negative regulation of steroid metabolic process [IC]
- negative regulation of transferase activity [IDA]
- retinoic acid metabolic process [IC]
- steroid metabolic process [IC]
- xenobiotic glucuronidation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CRYAB
CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2
crystallin, alpha B
GO Process (6)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.99821757 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.998217569937261, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID