BAIT
P2RX5
LRH-1, P2X5, P2X5R
purinergic receptor P2X, ligand-gated ion channel, 5
GO Process (9)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- cation transmembrane transport [NAS]
- cation transport [NAS]
- ion transmembrane transport [TAS]
- nervous system development [TAS]
- positive regulation of calcium ion transport into cytosol [NAS]
- positive regulation of calcium-mediated signaling [NAS]
- purinergic nucleotide receptor signaling pathway [NAS]
- signal transduction [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
POMK
MDDGA12, MDDGC12, SGK196
protein-O-mannose kinase
GO Process (3)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Status: Pre-Publication Dataset
Quantitative Score
- 0.589016363 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.589016362989316, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Curated By
- BioGRID