AZIN2
Gene Ontology Biological Process
- agmatine biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- negative regulation of protein catabolic process [IDA, ISS]
- polyamine metabolic process [TAS]
- positive regulation of catalytic activity [ISS]
- positive regulation of polyamine transmembrane transport [ISS]
- putrescine transport [ISS]
- small molecule metabolic process [TAS]
- spermatogenesis [NAS]
- trans-Golgi network membrane organization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
OAZ2
Gene Ontology Biological Process
- cellular nitrogen compound metabolic process [TAS]
- negative regulation of catalytic activity [IDA, TAS]
- polyamine metabolic process [TAS]
- positive regulation of intracellular protein transport [ISS]
- positive regulation of protein catabolic process [ISS]
- regulation of cellular amino acid metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network of Human Protein Interactions: Additional Unpublished AP-MS Results (Pre-Publication)
As part of an ongoing effort led by Steve Gygi, Wade Harper, and Ed Huttlin in the Department of Cell Biology at Harvard Medical School, we are systematically profiling the interactions among human proteins using affinity purification mass spectrometry. In this effort, HA-tagged bait proteins obtained from the human ORFeome collection (version 8.1; Marc Vidal) are expressed individually in human ... [more]
Quantitative Score
- 0.999999971 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex HCT (unpublished interaction)
- BioPlex HCT HCT116 cells CompPASS score = 0.99999997050522, threshold = 0.362. Quantitative scores are calculated by CompPASS-Plus (Huttlin et al. Cell 2015, PMID: 26186194). The 0.362 threshold represents the top 2% of scores in HCT116.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AZIN2 OAZ2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 2222698 | |
| AZIN2 OAZ2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9999 | BioGRID | 3116264 |
Curated By
- BioGRID