BAIT
CG14692
Dmel\CG14692, Dmel_CG14692
CG14692 gene product from transcript CG14692-RD
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY
RPR
CG4319, Dmel\CG4319, anon-WO0162936.19, rp, Dmel_CG4319
reaper
GO Process (20)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- apoptotic process [IDA, IEP, IMP, NAS, TAS]
- apoptotic signaling pathway [IGI, IMP]
- cell death [IMP]
- cellular response to gamma radiation [IMP]
- cellular response to ionizing radiation [IDA]
- ecdysone-mediated induction of salivary gland cell autophagic cell death [IEP]
- imaginal disc-derived male genitalia morphogenesis [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- intrinsic apoptotic signaling pathway in response to osmotic stress [TAS]
- larval central nervous system remodeling [TAS]
- larval midgut cell programmed cell death [IGI, NAS]
- negative regulation of neuron apoptotic process [IMP]
- nurse cell apoptotic process [TAS]
- positive regulation of cysteine-type endopeptidase activity [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [IDA]
- positive regulation of protein ubiquitination [IDA]
- positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IGI]
- programmed cell death [IMP, TAS]
- regulation of protein catabolic process [IDA]
- salivary gland cell autophagic cell death [IGI, NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID