MOT1
Gene Ontology Biological Process
- negative regulation of transcription, DNA-templated [IMP]
- rRNA processing [IMP]
- regulation of RNA polymerase II transcriptional preinitiation complex assembly [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- transcription of nuclear large rRNA transcript from RNA polymerase I promoter [IDA, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RSC9
Gene Ontology Biological Process
- ATP-dependent chromatin remodeling [IDA]
- G2/M transition of mitotic cell cycle [IMP]
- cellular response to hydrogen peroxide [IDA]
- chromatin remodeling [IPI]
- nucleosome disassembly [IDA]
- rRNA transcription [IMP]
- regulation of transcription from RNA polymerase II promoter [IMP]
- transcription elongation from RNA polymerase II promoter [IDA]
- transfer RNA gene-mediated silencing [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A proteomics analysis of yeast Mot1p protein-protein associations: insights into mechanism.
Yeast Mot1p, a member of the Snf2 ATPase family of proteins, is a transcriptional regulator that has the unusual ability to both repress and activate mRNA gene transcription. To identify interactions with other proteins that may assist Mot1p in its regulatory processes, Mot1p was purified from replicate yeast cell extracts, and Mot1p-associated proteins were identified by coupled multidimensional liquid chromatography ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RSC9 MOT1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1716 | BioGRID | 1946534 |
Curated By
- BioGRID