BAIT
TMEM192
transmembrane protein 192
GO Process (0)
GO Function (1)
GO Component (9)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC2A1
DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1, GLUT1DS, HTLVR, PED
solute carrier family 2 (facilitated glucose transporter), member 1
GO Process (11)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- L-ascorbic acid metabolic process [TAS]
- carbohydrate metabolic process [TAS]
- energy reserve metabolic process [TAS]
- glucose transport [IDA, TAS]
- hexose transport [TAS]
- protein complex assembly [IDA]
- regulation of insulin secretion [TAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- vitamin metabolic process [TAS]
- water-soluble vitamin metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Autophagy deficiency in fed conditions leads to the formation of protein inclusions highlighting the contribution of this lysosomal delivery route to cellular proteostasis. Selective autophagy pathways exist that clear accumulated and aggregated ubiquitinated proteins. Receptors for this type of autophagy (aggrephagy) include p62, NBR1, TOLLIP, and OPTN, which possess LC3-interacting regions and ubiquitin-binding domains (UBDs), thus working as a bridge ... [more]
Mol Cell Dec. 18, 2020; 81(6);1337-1354.e8 [Pubmed: 33545068]
Throughput
- High Throughput
Additional Notes
- Affinity capture MS carried out to identify high-confidence protein interactions
Curated By
- BioGRID