BAIT
CNR2
CB-2, CB2, CX5, RP11-4M23.1
cannabinoid receptor 2 (macrophage)
GO Process (3)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
DHCR24
DCE, Nbla03646, SELADIN1, seladin-1
24-dehydrocholesterol reductase
GO Process (11)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- apoptotic process [NAS]
- cell cycle arrest [NAS]
- cholesterol biosynthetic process [IMP, ISS, TAS]
- negative regulation of apoptotic process [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- oxidation-reduction process [IMP]
- regulation of neuron death [NAS]
- response to oxidative stress [IEP]
- skin development [ISS]
- small molecule metabolic process [TAS]
- tissue development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.
The endocannabinoid system (ECS) consists particularly of cannabinoid receptors 1 and 2 (CB1 and CB2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. It acts in a variety of organs and disease states ranging from cancer progression over neuropathic pain to neurodegeneration. Protein components engaged in the signaling, trafficking, and homeostasis machinery of the G-protein coupled CB2, ... [more]
Front Mol Neurosci Oct. 17, 2019; 12();224 [Pubmed: 31616248]
Throughput
- High Throughput
Curated By
- BioGRID