BAIT
CNR2
CB-2, CB2, CX5, RP11-4M23.1
cannabinoid receptor 2 (macrophage)
GO Process (3)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
EMD
EDMD, LEMD5, STA, XX-FW88778H2.1
emerin
GO Process (10)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- cellular response to growth factor stimulus [IMP]
- mitotic cell cycle [TAS]
- mitotic nuclear envelope disassembly [TAS]
- mitotic nuclear envelope reassembly [TAS]
- muscle contraction [TAS]
- muscle organ development [TAS]
- negative regulation of catenin import into nucleus [IMP]
- negative regulation of fibroblast proliferation [IMP]
- positive regulation of protein export from nucleus [IMP]
- regulation of canonical Wnt signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.
The endocannabinoid system (ECS) consists particularly of cannabinoid receptors 1 and 2 (CB1 and CB2), their endogenous ligands, and enzymes that synthesize and degrade their ligands. It acts in a variety of organs and disease states ranging from cancer progression over neuropathic pain to neurodegeneration. Protein components engaged in the signaling, trafficking, and homeostasis machinery of the G-protein coupled CB2, ... [more]
Front Mol Neurosci Oct. 17, 2019; 12();224 [Pubmed: 31616248]
Throughput
- High Throughput
Curated By
- BioGRID