BAIT
BCOR
ANOP2, MAA2, MCOPS2
BCL6 corepressor
GO Process (11)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- heart development [IMP]
- histone H2A monoubiquitination [IDA]
- negative regulation of bone mineralization [IMP]
- negative regulation of histone H3-K36 methylation [IMP]
- negative regulation of histone H3-K4 methylation [IMP]
- negative regulation of tooth mineralization [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- odontogenesis [IMP]
- palate development [IMP]
- specification of axis polarity [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ARID3B
BDP, DRIL2
AT rich interactive domain 3B (BRIGHT-like)
GO Process (0)
GO Function (1)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [NAS]
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.
Glucocorticoid (GC) receptor (GR) is a key transcription factor (TF) that regulates vital metabolic and anti-inflammatory processes. We have identified BCL6 corepressor (BCOR) as a dexamethasone-stimulated interaction partner of GR. BCOR is a component of non-canonical polycomb repressor complex 1.1 (ncPCR1.1) and linked to different developmental disorders and cancers, but the role of BCOR in GC signaling is poorly characterized. ... [more]
J Steroid Biochem Mol Biol Dec. 01, 2020; 210();105873 [Pubmed: 33722704]
Throughput
- Low Throughput
Curated By
- BioGRID