BAIT

ROPGEF1

ATROPGEF1, F22I13.200, F22I13_200, KINASE PARTNER PROTEIN-LIKE, KPP-LIKE, rho guanyl-nucleotide exchange factor 1, AT4G38430
Rop guanine nucleotide exchange factor 1
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

ARAC5

ARABIDOPSIS THALIANA GERANYLGERANYLATED PROTEIN 3, ATGP3, ATROP4, RAC-LIKE GTP BINDING PROTEIN, RAC-like GTP binding protein 5, RHO-LIKE GTP BINDING PROTEIN 4, ROP4, AT1G75840
Rac-like GTP-binding protein ARAC5
GO Process (0)
GO Function (4)
GO Component (5)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A new family of RhoGEFs activates the Rop molecular switch in plants.

Berken A, Thomas C, Wittinghofer A

In plants, the small GTP-binding proteins called Rops work as signalling switches that control growth, development and plant responses to various environmental stimuli. Rop proteins (Rho of plants, Rac-like and AtRac in Arabidopsis thaliana) belong to the Rho family of Ras-related GTP-binding proteins that turn on signalling pathways by switching from a GDP-bound inactive to a GTP-bound active conformation. Activation ... [more]

Nature Aug. 25, 2005; 436(7054);1176-80 [Pubmed: 15980860]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ROPGEF1 ARAC5
Biochemical Activity
Biochemical Activity

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Low-BioGRID
331280

Curated By

  • BioGRID