BAIT

ROPGEF1

ATROPGEF1, F22I13.200, F22I13_200, KINASE PARTNER PROTEIN-LIKE, KPP-LIKE, rho guanyl-nucleotide exchange factor 1, AT4G38430
Rop guanine nucleotide exchange factor 1
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)
PREY

ARAC1

ATGP2, ATRAC1, ATROP3, Arabidopsis RAC-like 1, RHO-RELATED GTPASES FROM PLANTS 3, ROP3, T17A5.14, T17A5_14, AT2G17800
Rac-like GTP-binding protein ARAC1
GO Process (2)
GO Function (1)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Arabidopsis thaliana (Columbia)

Biochemical Activity

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

A new family of RhoGEFs activates the Rop molecular switch in plants.

Berken A, Thomas C, Wittinghofer A

In plants, the small GTP-binding proteins called Rops work as signalling switches that control growth, development and plant responses to various environmental stimuli. Rop proteins (Rho of plants, Rac-like and AtRac in Arabidopsis thaliana) belong to the Rho family of Ras-related GTP-binding proteins that turn on signalling pathways by switching from a GDP-bound inactive to a GTP-bound active conformation. Activation ... [more]

Nature Aug. 25, 2005; 436(7054);1176-80 [Pubmed: 15980860]

Throughput

  • Low Throughput

Additional Notes

  • guanine nucleotide exchange

Curated By

  • BioGRID