BAIT
PAXIP1
D5Ertd149e, PTIP
PAX interacting (with transcription-activation domain) protein 1
GO Process (11)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- adipose tissue development [IMP]
- cellular response to DNA damage stimulus [IDA]
- chorion development [IMP]
- endothelial cell migration [IMP]
- positive regulation of histone H3-K36 methylation [IMP]
- positive regulation of histone H3-K4 methylation [IMP]
- positive regulation of histone acetylation [IMP]
- positive regulation of isotype switching [IMP]
- positive regulation of protein ubiquitination [IMP]
- positive regulation of transcription initiation from RNA polymerase II promoter [IMP]
- vasculogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DYNLL1
DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1
dynein, light chain, LC8-type 1
GO Process (11)
GO Function (1)
GO Component (11)
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- actin cytoskeleton organization [TAS]
- anatomical structure morphogenesis [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- apoptotic process [TAS]
- female gamete generation [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- mitotic cell cycle [TAS]
- negative regulation of phosphorylation [IDA]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- substantia nigra development [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.
Methylation of lysine 4 on histone H3 (H3K4) at promoters is tightly linked to transcriptional regulation in human cells. At least six different COMPASS-like multisubunit (SET1/MLL) complexes that contain methyltransferase activity for H3K4 have been described, but a comprehensive and quantitative analysis of these SET1/MLL complexes is lacking. We applied label-free quantitative mass spectrometry to determine the subunit composition and ... [more]
Mol Cell Biol May. 01, 2013; 33(10);2067-77 [Pubmed: 23508102]
Throughput
- High Throughput
Curated By
- BioGRID