BAIT
T
SAVA, TFT, RP11-459F1.1
T, brachyury homolog (mouse)
GO Process (8)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- anterior/posterior axis specification, embryo [TAS]
- heart morphogenesis [IDA]
- mesoderm development [TAS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [IDA]
- primitive streak formation [NAS]
- signal transduction [NAS]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISS]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [ISS]
- sequence-specific DNA binding transcription factor activity [NAS]
- RNA polymerase II activating transcription factor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISS]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding [ISS]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [ISS]
- sequence-specific DNA binding transcription factor activity [NAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
EHMT2
BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, DAAP-66K18.3
euchromatic histone-lysine N-methyltransferase 2
GO Process (6)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID