BAIT
CPEB1
CPE-BP1, CPEB, CPEB-1, hCPEB-1
cytoplasmic polyadenylation element binding protein 1
GO Process (4)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
RC3H1
RNF198, ROQUIN, RP5-1198E17.5
ring finger and CCCH-type domains 1
GO Process (11)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- cytoplasmic mRNA processing body assembly [ISS]
- negative regulation of B cell proliferation [ISS]
- negative regulation of T-helper cell differentiation [ISS]
- negative regulation of activated T cell proliferation [ISS]
- negative regulation of germinal center formation [ISS]
- nuclear-transcribed mRNA catabolic process [ISS]
- posttranscriptional regulation of gene expression [ISS]
- protein ubiquitination [TAS]
- regulation of T cell receptor signaling pathway [ISS]
- regulation of germinal center formation [ISS]
- regulation of mRNA stability [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID