BAIT
GATA3
HDR, HDRS
GATA binding protein 3
GO Process (58)
GO Function (13)
GO Component (4)
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISS]
- TOR signaling [ISS]
- anatomical structure formation involved in morphogenesis [ISS]
- anatomical structure morphogenesis [TAS]
- aortic valve morphogenesis [ISS]
- blood coagulation [TAS]
- canonical Wnt signaling pathway involved in metanephric kidney development [ISS]
- cardiac right ventricle morphogenesis [ISS]
- cell fate determination [ISS]
- cellular response to interferon-alpha [IEP]
- cellular response to interleukin-4 [IEP]
- cellular response to tumor necrosis factor [IEP]
- defense response [TAS]
- ear development [IMP]
- kidney development [IMP]
- lymphocyte migration [IDA]
- male gonad development [ISS]
- mesenchymal to epithelial transition [IDA]
- mesonephros development [ISS]
- negative regulation of cell cycle [IMP]
- negative regulation of cell motility [IMP]
- negative regulation of cell proliferation [ISS]
- negative regulation of cell proliferation involved in mesonephros development [ISS]
- negative regulation of endothelial cell apoptotic process [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation [ISS]
- negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation [ISS]
- negative regulation of inflammatory response [IMP]
- negative regulation of mammary gland epithelial cell proliferation [IDA]
- negative regulation of transcription, DNA-templated [IMP]
- nephric duct formation [ISS]
- nephric duct morphogenesis [ISS]
- norepinephrine biosynthetic process [ISS]
- pharyngeal system development [ISS]
- phosphatidylinositol 3-kinase signaling [ISS]
- positive regulation of T cell differentiation [ISS]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of interleukin-13 secretion [IDA, IMP]
- positive regulation of interleukin-4 production [ISS]
- positive regulation of interleukin-5 secretion [IDA]
- positive regulation of protein kinase B signaling [IMP]
- positive regulation of signal transduction [IMP]
- positive regulation of thyroid hormone generation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISS]
- positive regulation of transcription regulatory region DNA binding [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISS]
- positive regulation of ureteric bud formation [ISS]
- regulation of cellular response to X-ray [IMP]
- regulation of cytokine biosynthetic process [ISS]
- regulation of nephron tubule epithelial cell differentiation [ISS]
- response to estrogen [IEP]
- response to virus [IEP]
- signal transduction [ISS]
- sympathetic nervous system development [ISS]
- transcription from RNA polymerase II promoter [TAS]
- ureteric bud formation [ISS]
- uterus development [ISS]
- ventricular septum development [ISS]
Gene Ontology Molecular Function- DNA binding [TAS]
- E-box binding [IDA]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IMP]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- nucleic acid binding transcription factor activity [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- DNA binding [TAS]
- E-box binding [IDA]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IMP]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- nucleic acid binding transcription factor activity [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
RPL34
L34
ribosomal protein L34
GO Process (13)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID