BAIT
PAX2
FSGS7, PAPRS, RP11-179B2.1
paired box 2
GO Process (62)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- axonogenesis [TAS]
- brain morphogenesis [ISS]
- branching involved in ureteric bud morphogenesis [IEP, ISS]
- camera-type eye development [ISS]
- cell fate determination [ISS]
- cellular response to glucose stimulus [ISS]
- cellular response to hydrogen peroxide [ISS]
- cellular response to retinoic acid [ISS]
- cochlea development [ISS]
- cochlea morphogenesis [ISS]
- glial cell differentiation [ISS]
- inner ear morphogenesis [ISS]
- mesenchymal to epithelial transition [ISS]
- mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- mesodermal cell fate specification [ISS]
- mesonephros development [ISS]
- metanephric collecting duct development [ISS]
- metanephric distal convoluted tubule development [ISS]
- metanephric epithelium development [IEP]
- metanephric mesenchymal cell differentiation [ISS]
- metanephric mesenchyme development [ISS]
- metanephric nephron tubule formation [ISS]
- negative regulation of apoptotic process [IDA, IMP]
- negative regulation of apoptotic process involved in metanephric collecting duct development [ISS]
- negative regulation of apoptotic process involved in metanephric nephron tubule development [ISS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- negative regulation of cytolysis [IMP]
- negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [ISS]
- negative regulation of mesenchymal cell apoptotic process involved in metanephros development [ISS]
- negative regulation of programmed cell death [ISS]
- negative regulation of reactive oxygen species metabolic process [IDA]
- negative regulation of transcription, DNA-templated [IMP]
- nephric duct formation [ISS]
- neural tube closure [ISS]
- optic chiasma development [ISS]
- optic cup morphogenesis involved in camera-type eye development [ISS]
- optic nerve development [ISS]
- optic nerve morphogenesis [ISS]
- optic nerve structural organization [ISS]
- positive regulation of branching involved in ureteric bud morphogenesis [ISS]
- positive regulation of epithelial cell proliferation [IDA]
- positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [ISS]
- positive regulation of metanephric DCT cell differentiation [ISS]
- positive regulation of metanephric glomerulus development [ISS]
- positive regulation of optic nerve formation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISS]
- positive regulation of transcription, DNA-templated [IDA]
- pronephric field specification [ISS]
- pronephros development [ISS]
- protein kinase B signaling [ISS]
- reactive oxygen species metabolic process [ISS]
- regulation of metanephric nephron tubule epithelial cell differentiation [ISS]
- regulation of metanephros size [IMP]
- retinal pigment epithelium development [ISS]
- stem cell differentiation [ISS]
- transcription from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [ISS]
- ureter development [ISS]
- ureter maturation [ISS]
- urogenital system development [ISS]
- vestibulocochlear nerve formation [ISS]
- visual perception [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID