BAIT
SOX17
VUR3
SRY (sex determining region Y)-box 17
GO Process (25)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- angiogenesis [ISS]
- cardiac cell fate determination [IMP]
- cardiogenic plate morphogenesis [ISS]
- embryonic foregut morphogenesis [ISS]
- embryonic heart tube development [ISS]
- embryonic heart tube morphogenesis [ISS]
- endocardial cell differentiation [ISS]
- endocardium formation [ISS]
- endoderm formation [IDA]
- endodermal digestive tract morphogenesis [ISS]
- heart formation [TAS]
- heart looping [ISS]
- mRNA transcription from RNA polymerase II promoter [IDA]
- negative regulation of canonical Wnt signaling pathway [IMP]
- negative regulation of cell growth [IMP]
- outflow tract morphogenesis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- protein destabilization [IMP]
- protein stabilization [IMP]
- regulation of embryonic development [ISS]
- regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification [ISS]
- regulation of transcription, DNA-templated [ISS]
- renal system development [IMP]
- vasculogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SSBP1
Mt-SSB, SOSS-B1, SSBP, mtSSB
single-stranded DNA binding protein 1, mitochondrial
GO Process (1)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID