BAIT

CPEB1

CPE-BP1, CPEB, CPEB-1, hCPEB-1

cytoplasmic polyadenylation element binding protein 1

GO Process (4)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

cellular response to amino acid stimulus [ISS]

cellular response to hypoxia [IDA]

cellular response to insulin stimulus [IDA]

negative regulation of cytoplasmic translation [IMP]

Gene Ontology Molecular Function

mRNA 3'-UTR AU-rich region binding [ISS]
translation repressor activity, nucleic acid binding [ISS]

Gene Ontology Cellular Component

cytoplasm [ISS]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

YBX1

BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1

Y box binding protein 1

Human Papilloma Virus (HPV) Project

GO Process (7)

GO Function (8)

GO Component (11)

Gene Ontology Biological Process

CRD-mediated mRNA stabilization [IMP]

RNA splicing [TAS]

gene expression [TAS]

mRNA splicing, via spliceosome [TAS]

positive regulation of transcription from RNA polymerase II promoter [IDA]

regulation of transcription, DNA-templated [IDA]

transcription from RNA polymerase II promoter [TAS]

Gene Ontology Molecular Function

DNA binding [IDA, TAS]
RNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
double-stranded DNA binding [TAS]
poly(A) RNA binding [IDA]
protein binding [IPI]
sequence-specific DNA binding transcription factor activity [TAS]

Gene Ontology Cellular Component

CRD-mediated mRNA stability complex [IDA]

U12-type spliceosomal complex [IDA]

cytoplasm [IDA]

cytoplasmic stress granule [IDA]

extracellular vesicular exosome [IDA]

histone pre-mRNA 3'end processing complex [ISS]

intracellular membrane-bounded organelle [IDA]

nuclear membrane [IDA]

nucleoplasm [TAS]

ribonucleoprotein complex [IDA]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Human transcription factor protein interaction networks

Goos H, Kinnunen M, Salokas K, Tan Z, Liu X, Yadav L, Zhang Q, Wei G-H, Varjosalo M

Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]

Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]

Throughput

High Throughput

Additional Notes

Filtered using SAINT software tools (cutoff 0.74) and CRAPome database

Curated By

BioGRID