BAIT
GATA2
DCML, IMD21, MONOMAC, NFE1B
GATA binding protein 2
GO Process (10)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- blood coagulation [TAS]
- eosinophil fate commitment [IDA]
- negative regulation of Notch signaling pathway [IDA]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fat cell proliferation [IMP]
- negative regulation of neural precursor cell proliferation [IDA]
- positive regulation of angiogenesis [IDA]
- positive regulation of phagocytosis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA, TAS]
Homo sapiens
PREY
SPTAN1
EIEE5, NEAS, SPTA2
spectrin, alpha, non-erythrocytic 1
GO Process (3)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID