BAIT
GATA4
ASD2, TACHD, TOF, VSD1
GATA binding protein 4
GO Process (23)
GO Function (10)
GO Component (3)
Gene Ontology Biological Process
- atrial septum morphogenesis [IMP]
- atrial septum primum morphogenesis [ISS]
- atrial septum secundum morphogenesis [IMP]
- blood coagulation [TAS]
- cardiac right ventricle morphogenesis [ISS]
- cardiac ventricle morphogenesis [TAS]
- cell-cell signaling [ISS]
- embryonic foregut morphogenesis [ISS]
- embryonic heart tube anterior/posterior pattern specification [ISS]
- endocardial cushion development [IMP, ISS]
- endoderm development [TAS]
- heart looping [ISS]
- intestinal epithelial cell differentiation [IDA]
- male gonad development [IEP, IMP]
- positive regulation of angiogenesis [ISS]
- positive regulation of cardioblast differentiation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISS]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- positive regulation vascular endothelial growth factor production [ISS]
- regulation of transcription, DNA-templated [ISS]
- response to drug [IMP]
- transcription from RNA polymerase II promoter [ISS]
- ventricular septum development [ISS]
Gene Ontology Molecular Function- DNA binding [IDA, ISS]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- activating transcription factor binding [ISS]
- co-SMAD binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IDA, ISS]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- activating transcription factor binding [ISS]
- co-SMAD binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
TPM4
HEL-S-108
tropomyosin 4
GO Process (4)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID