BAIT
GLI3
ACLS, GCPS, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
GLI family zinc finger 3
GO Process (16)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- T cell differentiation in thymus [ISS]
- embryonic digestive tract development [TAS]
- embryonic digit morphogenesis [TAS]
- limb morphogenesis [IMP]
- negative regulation of alpha-beta T cell differentiation [ISS]
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of smoothened signaling pathway [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- negative thymic T cell selection [ISS]
- nose morphogenesis [TAS]
- positive regulation of alpha-beta T cell differentiation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription, DNA-templated [ISS]
- smoothened signaling pathway [TAS]
- thymocyte apoptotic process [ISS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- beta-catenin binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
- beta-catenin binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
Homo sapiens
PREY
RPS11
S11
ribosomal protein S11
GO Process (13)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID