BAIT
SOX15
SOX20, SOX26, SOX27
SRY (sex determining region Y)-box 15
GO Process (12)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- cell differentiation [ISS]
- chromatin organization [NAS]
- male gonad development [TAS]
- myoblast development [ISS]
- negative regulation of striated muscle tissue development [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of G0 to G1 transition [ISS]
- positive regulation of myoblast proliferation [ISS]
- positive regulation of satellite cell activation involved in skeletal muscle regeneration [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
RPS13
S13
ribosomal protein S13
GO Process (14)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- negative regulation of RNA splicing [IDA]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID