BAIT
SOX6
HSSOX6, SOXD
SRY (sex determining region Y)-box 6
GO Process (6)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- cellular response to transforming growth factor beta stimulus [IDA]
- muscle organ development [NAS]
- positive regulation of cartilage development [IDA]
- positive regulation of chondrocyte differentiation [IDA]
- positive regulation of mesenchymal stem cell differentiation [IDA]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA, NAS]
Homo sapiens
PREY
RPS13
S13
ribosomal protein S13
GO Process (14)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- negative regulation of RNA splicing [IDA]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here, we identify 6703 and 1536 protein-protein interactions for 109 different human TFs through proximity-dependent biotinylation (BioID) and affinity purification mass spectrometry (AP-MS), respectively. The BioID analysis identifies more high-confidence interactions, highlighting the transient and dynamic nature of many of the TF interactions. By performing clustering ... [more]
Nature Communications Feb. 09, 2022; (); [Pubmed: 35140242]
Throughput
- High Throughput
Additional Notes
- Filtered using SAINT software tools (cutoff 0.74) and CRAPome database
Curated By
- BioGRID