BAIT

NOG1

YPL093W

Putative GTPase; associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins

GO Process (4)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

assembly of large subunit precursor of preribosome [IMP]

rRNA processing [IMP]

ribosomal large subunit biogenesis [IDA, IMP]

ribosomal subunit export from nucleus [IMP, IPI]

Gene Ontology Molecular Function

GTP binding [ISS]

Gene Ontology Cellular Component

nucleolus [IDA]

preribosome, large subunit precursor [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Saccharomyces cerevisiae (S288c)

PREY

ITS2-1

ITS2

Non-coding region between RDN58 and RDN25; transcribed as part of the 35S rRNA precursor transcript; forms a stem-loop structure that is required for processing of the precursor transcript

GO Process (0)

GO Function (0)

GO Component (0)

SGD Alliance of Genome Resources Entrez Gene

Saccharomyces cerevisiae (S288c)

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.

Poell G, Pilsl M, Griesenbeck J, Tschochner H, Milkereit P

In yeast and human cells many of the ribosomal proteins (r-proteins) are required for the stabilisation and productive processing of rRNA precursors. Functional coupling of r-protein assembly with the stabilisation and maturation of subunit precursors potentially promotes the production of ribosomes with defined composition. To further decipher mechanisms of such an intrinsic quality control pathway we analysed here the contribution ... [more]

PLoS One Nov. 24, 2021; 16(11);e0252497 [Pubmed: 34813592]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary