BAIT
MAP1LC3A
ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, RP11-346K17.1
microtubule-associated protein 1 light chain 3 alpha
GO Process (5)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MTX1
MTX, MTXN, RP11-263K19.5
metaxin 1
GO Process (2)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.
Mitophagy is the degradation of surplus or damaged mitochondria by autophagy. In addition to programmed and stress-induced mitophagy, basal mitophagy processes exert organelle quality control. Here, we show that the sorting and assembly machinery (SAM) complex protein SAMM50 interacts directly with ATG8 family proteins and p62/SQSTM1 to act as a receptor for a basal mitophagy of components of the SAM ... [more]
J Cell Biol Dec. 02, 2020; 220(8); [Pubmed: 34037656]
Throughput
- Low Throughput
Curated By
- BioGRID