PREY

CDH13

CDHH, P105
cadherin 13
GO Process (24)
GO Function (4)
GO Component (7)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

SIK2 orchestrates actin-dependent host response upon Salmonella infection.

Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle KB, Muench C, Rajalingam K, Randow F, Choudhary C, Dikic I

Salmonella is an intracellular pathogen of a substantial global health concern. In order to identify key players involved in Salmonella infection, we performed a global host phosphoproteome analysis subsequent to bacterial infection. Thereby, we identified the kinase SIK2 as a central component of the host defense machinery upon Salmonella infection. SIK2 depletion favors the escape of bacteria from the Salmonella-containing ... [more]

Proc Natl Acad Sci U S A Dec. 11, 2020; 118(19); [Pubmed: 33947818]

Throughput

  • High Throughput

Curated By

  • BioGRID