BAIT
SIK2
LOH11CR1I, QIK, SNF1LK2
salt-inducible kinase 2
GO Process (4)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ARPC5
ARC16, dJ127C7.3, p16-Arc, RP1-127C7.3
actin related protein 2/3 complex, subunit 5, 16kDa
GO Process (5)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
SIK2 orchestrates actin-dependent host response upon Salmonella infection.
Salmonella is an intracellular pathogen of a substantial global health concern. In order to identify key players involved in Salmonella infection, we performed a global host phosphoproteome analysis subsequent to bacterial infection. Thereby, we identified the kinase SIK2 as a central component of the host defense machinery upon Salmonella infection. SIK2 depletion favors the escape of bacteria from the Salmonella-containing ... [more]
Proc Natl Acad Sci U S A Dec. 11, 2020; 118(19); [Pubmed: 33947818]
Throughput
- High Throughput
Curated By
- BioGRID