BAIT
CLUH
1300001I01Rik, Kiaa0664, mKIAA0664, RP23-194P5.1
clustered mitochondria (cluA/CLU1) homolog
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
DDX1
AA409185, DBP-RB
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
GO Process (8)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- double-strand break repair [ISO]
- nucleic acid phosphodiester bond hydrolysis [ISO]
- regulation of nucleic acid-templated transcription [ISO]
- response to exogenous dsRNA [IMP]
- response to virus [IMP]
- tRNA splicing, via endonucleolytic cleavage and ligation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.
Mitochondria require thousands of proteins to fulfill their essential function in energy production and other fundamental biological processes. These proteins are mostly encoded by the nuclear genome, translated in the cytoplasm before being imported into the organelle. RNA binding proteins (RBPs) are central players in the regulation of this process by affecting mRNA translation, stability, or localization. CLUH is an ... [more]
BMC Biol Jan. 10, 2022; 20(1);13 [Pubmed: 35012549]
Throughput
- High Throughput
Curated By
- BioGRID