BAIT
BCAS3
GAOB1, MAAB
breast carcinoma amplified sequence 3
GO Process (17)
GO Function (8)
GO Component (6)
Gene Ontology Biological Process
- Golgi organization [ISS]
- activation of Cdc42 GTPase activity [ISS]
- cellular response to estrogen stimulus [IDA]
- microtubule organizing center organization [ISS]
- negative regulation of Rho GTPase activity [ISS]
- negative regulation of focal adhesion assembly [ISS]
- positive regulation of Cdc42 GTPase activity [ISS]
- positive regulation of actin cytoskeleton reorganization [ISS]
- positive regulation of catalytic activity [IDA]
- positive regulation of endothelial cell migration [ISS]
- positive regulation of filopodium assembly [ISS]
- positive regulation of intracellular protein transport [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of establishment of cell polarity [ISS]
- response to starvation [IBA]
- tube formation [ISS]
- vesicle-mediated transport [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VIM
CTRCT30, HEL113, RP11-124N14.1
vimentin
GO Process (4)
GO Function (7)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
BCAS3 exhibits oncogenic properties by promoting CRL4A-mediated ubiquitination of p53 in breast cancer.
Breast cancer-amplified sequence 3 (BCAS3) was initially found to be amplified in human breast cancer (BRCA); however, there has been little consensus on the functions of BCAS3 in breast tumours.We analysed BCAS3 expression in BRCA using bio-information tools. Affinity purification and mass spectrometry were employed to identify BCAS3-associated proteins. GST pull-down and ubiquitination assays were performed to analyse the interaction ... [more]
Cell Prolif Aug. 01, 2021; 54(8);e13088 [Pubmed: 34240781]
Throughput
- Low Throughput
Curated By
- BioGRID