BAIT
NAP1L4
NAP1L4b, NAP2, NAP2L, hNAP2
nucleosome assembly protein 1-like 4
GO Process (0)
GO Function (3)
GO Component (1)
Gene Ontology Molecular Function
Homo sapiens
PREY
HIST1H2AE
H2A.1, H2A.2, H2A/a, H2AFA
histone cluster 1, H2ae
GO Process (0)
GO Function (1)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone.
Histones are thought to play a key role in regulating gene expression at the level of DNA packaging. Recent evidence suggests that transcriptional activation requires competition of transcription factors with histones for binding to regulatory regions and that there may be several mechanisms by which this is achieved. We have characterized a human nucleosome assembly protein, NAP-2, previously identified by ... [more]
Genomics Sep. 15, 1997; 44(3);253-65 [Pubmed: 9325046]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
HIST1H2AE NAP1L4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9711 | BioGRID | 3157196 |
Curated By
- BioGRID