BAIT
SALL1
HEL-S-89, HSAL1, Sal-1, TBS, ZNF794
spalt-like transcription factor 1
GO Process (25)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- adrenal gland development [IEP]
- branching involved in ureteric bud morphogenesis [ISS]
- embryonic digestive tract development [IMP]
- embryonic digit morphogenesis [IMP]
- gonad development [IEP]
- heart development [IMP]
- histone deacetylation [ISS]
- inductive cell-cell signaling [ISS]
- kidney development [IMP]
- kidney epithelium development [ISS]
- limb development [IMP]
- mesenchymal to epithelial transition involved in metanephros morphogenesis [IEP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- olfactory bulb interneuron differentiation [ISS]
- olfactory bulb mitral cell layer development [IMP]
- olfactory nerve development [ISS]
- outer ear morphogenesis [IMP]
- pituitary gland development [IEP]
- positive regulation of Wnt signaling pathway [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- ureteric bud development [ISS]
- ureteric bud invasion [ISS]
- ventricular septum development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BAZ1B
WBSCR10, WBSCR9, WSTF
bromodomain adjacent to zinc finger domain, 1B
GO Process (8)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [IDA]
- chromatin-mediated maintenance of transcription [ISS]
- double-strand break repair [ISS]
- heart morphogenesis [ISS]
- histone phosphorylation [IDA]
- peptidyl-tyrosine phosphorylation [IDA]
- regulation of transcription, DNA-templated [ISS]
- transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Identification of proximal SUMO-dependent interactors using SUMO-ID.
The fast dynamics and reversibility of posttranslational modifications by the ubiquitin family pose significant challenges for research. Here we present SUMO-ID, a technology that merges proximity biotinylation by TurboID and protein-fragment complementation to find SUMO-dependent interactors of proteins of interest. We develop an optimized split-TurboID version and show SUMO interaction-dependent labelling of proteins proximal to PML and RANGAP1. SUMO-dependent interactors ... [more]
Nat Commun Dec. 18, 2020; 12(1);6671 [Pubmed: 34795231]
Throughput
- High Throughput
Additional Notes
- Sumo-dependent interaction
Curated By
- BioGRID