BAIT

LUC7L2

CGI-74, LUC7B2, CGI-59
LUC7-like 2 (S. cerevisiae)
GO Process (0)
GO Function (3)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

HNRNPM

CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP M
heterogeneous nuclear ribonucleoprotein M
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CRISPR/Cas9 genome-wide screening identifies LUC7L2 that promotes radioresistance via autophagy in nasopharyngeal carcinoma cells.

Shen L, Li C, Chen F, Shen L, Li Z, Li N

Radioresistance emerges as the major obstacle to nasopharyngeal carcinoma (NPC) treatment, further understanding of underlying mechanisms is necessary to overcome the radioresistance and improve the therapeutic effect. In this study, we first identified a candidate radioresistant-related gene LUC7L2 via CRISPR/Cas9 high-throughput screening and quantitative proteomic approach. Overexpression of LUC7L2 in NPC cells promoted cell viability following exposure to ionizing radiation ... [more]

Cell Death Discov Dec. 14, 2021; 7(1);392 [Pubmed: 34907164]

Throughput

  • Low Throughput

Curated By

  • BioGRID