BAIT

RTI

BEST:LD28579, BcDNA:LD10657, CG7085, Dmel\CG7085, l(2)s5379, Dmel_CG7085

rotini

GO Process (0)

GO Function (0)

GO Component (0)

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

PREY

CG13186

AAF58585, BcDNA:AT11581, Dmel\CG13186, Dmel_CG13186

CG13186 gene product from transcript CG13186-RA

GO Process (0)

GO Function (0)

GO Component (0)

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders.

Sechi S, Karimpour-Ghahnavieh A, Frappaolo A, Di Francesco L, Piergentili R, Schinina E, D'Avino PP, Giansanti MG

Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes depends on phosphatidylinositol 4-phosphate [PI(4)P] and regulates Golgi architecture and vesicle trafficking. GOLPH3 overexpression has been correlated with poor prognosis in several cancers, but the molecular mechanisms that link GOLPH3 to malignant transformation are poorly understood. ... [more]

Cells Dec. 06, 2020; 10(9); [Pubmed: 34571985]

Throughput

High Throughput

Curated By

BioGRID