BAIT

CCDC71

coiled-coil domain containing 71
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

NAP1L4

NAP1L4b, NAP2, NAP2L, hNAP2
nucleosome assembly protein 1-like 4
GO Process (0)
GO Function (3)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

ATRX proximal protein associations boast roles beyond histone deposition.

Scott WA, Dhanji EZ, Dyakov BJA, Dreseris ES, Asa JS, Grange LJ, Mirceta M, Pearson CE, Stewart GS, Gingras AC, Campos EI

The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used proximity-dependent biotinylation (BioID) to identify proximal associations for ATRX. The proteomic screen captured known interactors, such as DAXX, NBS1, and PML, but also identified a range of new associating ... [more]

PLoS Genet Dec. 01, 2020; 17(11);e1009909 [Pubmed: 34780483]

Throughput

  • High Throughput

Curated By

  • BioGRID