BAIT
DGT2
CG16969, Dmel\CG16969, Dmel_CG16969
dim gamma-tubulin 2
GO Process (2)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
VPS20
CG4071, DmVPS20, Dmel\CG4071, ESCRT-III, anon-EST:Posey40, Dmel_CG4071
Vacuolar protein sorting 20
GO Process (8)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- endosome transport via multivesicular body sorting pathway [IMP]
- epithelium development [IMP]
- germarium-derived female germ-line cyst formation [IMP]
- negative regulation of epidermal growth factor receptor signaling pathway [IMP]
- negative regulation of epithelial cell proliferation [IMP]
- ovarian follicle cell stalk formation [IMP]
- regulation of Notch signaling pathway [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID