BAIT
CTPS1
CTPS, IMD24
CTP synthase 1
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- B cell proliferation [IMP]
- CTP biosynthetic process [IDA, IMP]
- T cell proliferation [IMP]
- nucleobase-containing compound metabolic process [TAS]
- nucleobase-containing small molecule interconversion [TAS]
- nucleobase-containing small molecule metabolic process [TAS]
- response to drug [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- CTP synthase activity [EXP, IDA, IGI, IMP]
- CTP synthase activity [EXP, IDA, IGI, IMP]
Homo sapiens
PREY
GLUL
GLNS, GS, PIG43, PIG59
glutamate-ammonia ligase
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically map the localization and interactions of human proteins. Our approach provides a data-driven description of the molecular and spatial networks that organize the proteome. Unsupervised clustering of these networks delineates ... [more]
Science Dec. 11, 2021; 375(6585);eabi6983 [Pubmed: 35271311]
Throughput
- High Throughput
Additional Notes
- Bait generated from library of CRISPR-edited human embryonic kidney (HEK) 293T cell lines harboring fluorescent tags on individual proteins
Curated By
- BioGRID