DYNLL2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KANK1
Gene Ontology Biological Process
- negative regulation of Rho protein signal transduction [IMP]
- negative regulation of actin filament polymerization [IDA]
- negative regulation of cell migration [IMP]
- negative regulation of insulin receptor signaling pathway [IMP]
- negative regulation of lamellipodium morphogenesis [IDA]
- negative regulation of neuron projection development [IDA]
- negative regulation of ruffle assembly [IDA]
- negative regulation of substrate adhesion-dependent cell spreading [IDA]
- positive regulation of Wnt signaling pathway [IDA]
- positive regulation of catenin import into nucleus [IMP]
- positive regulation of wound healing [IMP]
- regulation of establishment of cell polarity [IMP]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically map the localization and interactions of human proteins. Our approach provides a data-driven description of the molecular and spatial networks that organize the proteome. Unsupervised clustering of these networks delineates ... [more]
Throughput
- High Throughput
Additional Notes
- Bait generated from library of CRISPR-edited human embryonic kidney (HEK) 293T cell lines harboring fluorescent tags on individual proteins
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
DYNLL2 KANK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3226890 | |
DYNLL2 KANK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3088322 |
Curated By
- BioGRID