BAIT
HMGB2
HMG2
high mobility group box 2
GO Process (22)
GO Function (12)
GO Component (7)
Gene Ontology Biological Process
- DNA ligation involved in DNA repair [ISS]
- DNA topological change [ISS]
- V(D)J recombination [ISS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- base-excision repair, DNA ligation [IDA]
- cell chemotaxis [IDA]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cellular response to lipopolysaccharide [IEP]
- chromatin organization [NAS]
- chromatin remodeling [IBA]
- negative regulation of transcription, DNA-templated [IDA]
- nucleosome assembly [NAS]
- positive chemotaxis [IDA]
- positive regulation of DNA binding [IDA]
- positive regulation of endothelial cell proliferation [IDA]
- positive regulation of erythrocyte differentiation [IMP]
- positive regulation of megakaryocyte differentiation [IMP]
- positive regulation of nuclease activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IMP]
- DNA binding, bending [IDA]
- RAGE receptor binding [IGI]
- chemoattractant activity [IDA]
- chromatin binding [IBA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription regulatory region DNA binding [IDA]
- DNA binding [IMP]
- DNA binding, bending [IDA]
- RAGE receptor binding [IGI]
- chemoattractant activity [IDA]
- chromatin binding [IBA]
- damaged DNA binding [IDA]
- double-stranded DNA binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [ISS]
- transcription regulatory region DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS7
DBA8, S7
ribosomal protein S7
GO Process (16)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- cytoplasmic translation [IBA]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- rRNA processing [IMP]
- ribosomal small subunit biogenesis [IMP]
- translation [IC, NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically map the localization and interactions of human proteins. Our approach provides a data-driven description of the molecular and spatial networks that organize the proteome. Unsupervised clustering of these networks delineates ... [more]
Science Dec. 11, 2021; 375(6585);eabi6983 [Pubmed: 35271311]
Throughput
- High Throughput
Additional Notes
- Bait generated from library of CRISPR-edited human embryonic kidney (HEK) 293T cell lines harboring fluorescent tags on individual proteins
Curated By
- BioGRID