BAIT
SPF45
CG17540, Dmel\CG17540, RBM17, dRBM17, dSPF45, spf-45, Dmel_CG17540
CG17540 gene product from transcript CG17540-RB
GO Process (4)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
NOS
CG6713, DNOS, DNOS1, Dmel\CG6713, drNOSoxy, nNOS, Dmel_CG6713
Nitric oxide synthase
GO Process (11)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- defense response [NAS]
- imaginal disc development [TAS]
- negative regulation of DNA replication [TAS]
- negative regulation of cell proliferation [TAS]
- nervous system development [IMP]
- nitric oxide biosynthetic process [TAS]
- nitric oxide mediated signal transduction [IBA]
- positive regulation of guanylate cyclase activity [IBA]
- regulation of heart rate [IMP]
- regulation of organ growth [TAS]
- synapse assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytosol [IBA]
- peroxisome [ISS]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID