BAIT
ECR
CG1765, CG8347, DEcR, Dhr23, DmEcR, Dmel\CG1765, ECR-C, EcR-A, EcR-B, EcR-B1, EcR1b, EcRA, EcRB-1, EcRB1, EcRC, EcdR, NR1H1, anon-WO0229075.1, lie, ms(2)06410, ms(2)42A, snt, Dmel_CG1765
Ecdysone receptor
GO Process (53)
GO Function (11)
GO Component (7)
Gene Ontology Biological Process
- Malpighian tubule morphogenesis [IMP]
- autophagy [IMP]
- axonogenesis [IMP]
- border follicle cell migration [IMP]
- cardiac muscle tissue development [IMP]
- cardioblast differentiation [IMP]
- cell adhesion [IMP]
- chitin-based embryonic cuticle biosynthetic process [IMP]
- dendrite morphogenesis [IMP, NAS]
- determination of adult lifespan [IMP]
- dorsal vessel heart proper cell fate commitment [IMP]
- ecdysis, chitin-based cuticle [IMP]
- ecdysone receptor-mediated signaling pathway [IMP]
- ecdysone-mediated induction of salivary gland cell autophagic cell death [NAS]
- epidermis development [IMP]
- germ cell development [IMP]
- germ-band shortening [IMP]
- hatching [IMP]
- head involution [IMP]
- histoblast morphogenesis [IMP]
- imaginal disc eversion [TAS]
- imaginal disc-derived wing morphogenesis [IGI, IMP]
- larval central nervous system remodeling [IMP, TAS]
- larval wandering behavior [IMP]
- long-term memory [IMP]
- metamorphosis [IMP]
- muscle organ development [IMP]
- mushroom body development [IGI, IMP]
- negative regulation of growth of symbiont in host [IMP]
- negative regulation of neuroblast proliferation [IMP]
- negative regulation of transcription, DNA-templated [TAS]
- neuron development [IMP]
- neuron remodeling [IMP]
- oogenesis [IMP, NAS]
- peripheral nervous system development [IMP]
- phagocytosis, engulfment [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of circadian sleep/wake cycle, sleep [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IGI, IMP]
- positive regulation of transcription, DNA-templated [IMP]
- pupariation [IMP]
- regulation of Malpighian tubule diameter [IMP]
- regulation of autophagy [IMP]
- regulation of cellular respiration [IMP]
- regulation of development, heterochronic [TAS]
- regulation of hemocyte proliferation [IMP]
- regulation of rhodopsin gene expression [IMP]
- regulation of transcription from RNA polymerase II promoter [IMP]
- response to cocaine [IGI]
- response to ecdysone [IMP]
- salivary gland cell autophagic cell death [IMP]
- sperm individualization [IMP]
- spermatid development [IMP]
Gene Ontology Molecular Function- DNA binding [IDA, NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IPI]
- RNA polymerase II transcription coactivator binding [IPI]
- core promoter binding [IDA]
- ecdysteroid hormone receptor activity [IDA, IPI, NAS]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [NAS, TAS]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI]
- repressing transcription factor binding [IPI]
- steroid binding [NAS]
- transcription regulatory region sequence-specific DNA binding [IDA]
- DNA binding [IDA, NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IPI]
- RNA polymerase II transcription coactivator binding [IPI]
- core promoter binding [IDA]
- ecdysteroid hormone receptor activity [IDA, IPI, NAS]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [NAS, TAS]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI]
- repressing transcription factor binding [IPI]
- steroid binding [NAS]
- transcription regulatory region sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
SPN42DD
CG9456, Dmel\CG9456, Spn1, sp1, Dmel_CG9456
Serpin 42Dd
GO Process (6)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID