RAB1B
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
COG3
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IDA]
- Golgi organization [IGI, IMP]
- intra-Golgi vesicle-mediated transport [IDA]
- protein glycosylation [IMP]
- protein localization to organelle [IMP]
- protein stabilization [IMP]
- retrograde transport, vesicle recycling within Golgi [IBA]
- retrograde vesicle-mediated transport, Golgi to ER [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Elucidating the wiring diagram of the human cell is a central goal of the postgenomic era. We combined genome engineering, confocal live-cell imaging, mass spectrometry, and data science to systematically map the localization and interactions of human proteins. Our approach provides a data-driven description of the molecular and spatial networks that organize the proteome. Unsupervised clustering of these networks delineates ... [more]
Throughput
- High Throughput
Additional Notes
- Bait generated from library of CRISPR-edited human embryonic kidney (HEK) 293T cell lines harboring fluorescent tags on individual proteins
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
RAB1B COG3 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 2197854 |
Curated By
- BioGRID