BAIT
PAN
CG17964, CG32005, CG34403, DTCF, Dm Pan, Dmel\CG34403, Dmel_CG17964, Dmel_CG32005, IA5, LEF-1, LEF/TCF, LEF/TCF-1, LEF1, LEF1/TCF, Lef, TCF, TCF/LEF, TCF/LEF1, Tcf-1, cTCF, d-TCF, l(4)102ABb, l(4)13, pan.dTCF, Dmel_CG34403
pangolin
GO Process (19)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- Wnt signaling pathway [NAS, TAS]
- canonical Wnt signaling pathway [IBA]
- embryonic pattern specification [IMP, ISS]
- heart development [IMP, TAS]
- imaginal disc-derived wing morphogenesis [IMP, ISS]
- mesodermal cell fate determination [TAS]
- negative regulation of Wnt signaling pathway [NAS]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IEP]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of Wnt signaling pathway [IMP, ISS]
- regulation of hemocyte differentiation [IMP, ISS]
- regulation of stem cell proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of transcription, DNA-templated [ISS]
- salivary gland morphogenesis [IMP]
- segment polarity determination [NAS]
- spiracle morphogenesis, open tracheal system [IMP, ISS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- beta-catenin binding [IBA]
- kinase binding [IPI]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- beta-catenin binding [IBA]
- kinase binding [IPI]
- protein binding [IPI]
- repressing transcription factor binding [IPI]
- sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
ALPH
CG1906, Dmel\CG1906, PP2Cb, SK3-1, pp2c99B, Dmel_CG1906
alphabet
GO Process (18)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
- compound eye morphogenesis [IMP]
- determination of adult lifespan [IMP]
- dorsal closure [IGI]
- imaginal disc fusion, thorax closure [IGI]
- imaginal disc-derived wing morphogenesis [IMP]
- mitotic cell cycle [IMP]
- negative regulation of ERK1 and ERK2 cascade [IGI]
- negative regulation of JNK cascade [IGI, IMP]
- negative regulation of MAP kinase activity [IMP]
- negative regulation of Ras protein signal transduction [IGI, IMP]
- negative regulation of stress-activated MAPK cascade [IGI]
- negative regulation of stress-activated protein kinase signaling cascade [IGI, IMP]
- positive regulation of R7 cell differentiation [IGI, IMP]
- protein dephosphorylation [NAS]
- regulation of p38MAPK cascade [IGI]
- response to UV-C [IMP]
- response to oxidative stress [IMP]
- response to paraquat [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID