FEM1B
Gene Ontology Biological Process
- branching involved in prostate gland morphogenesis [IMP]
- epithelial cell maturation [IMP]
- epithelial cell maturation involved in prostate gland development [IMP]
- protein ubiquitination [IDA, ISO]
- regulation of DNA damage checkpoint [ISO]
- regulation of extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- regulation of ubiquitin-protein transferase activity [ISO]
Gene Ontology Molecular Function
BEX4
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Structural basis and regulation of the reductive stress response.
Although oxidative phosphorylation is best known for producing ATP, it also yields reactive oxygen species (ROS) as invariant byproducts. Depletion of ROS below their physiological levels, a phenomenon known as reductive stress, impedes cellular signaling and has been linked to cancer, diabetes, and cardiomyopathy. Cells alleviate reductive stress by ubiquitylating and degrading the mitochondrial gatekeeper FNIP1, yet it is unknown ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID