Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.

Zhong Y, Long T, Gu CS, Tang JY, Gao LF, Zhu JX, Hu ZY, Wang X, Ma YD, Ding YQ, Li ZG, Wang XY

Tumour metastasis is a major reason accounting for the poor prognosis of colorectal cancer (CRC), and the discovery of targets in the primary tumours that can predict the risk of CRC metastasis is now urgently needed. In this study, we identified autophagy-related protein 9B (ATG9B) as a key potential target gene for CRC metastasis. High expression of ATG9B in tumour ... [more]

Cell Death Differ Dec. 01, 2020; 28(12);3251-3269 [Pubmed: 34131310]

Throughput

  • High Throughput

Curated By

  • BioGRID