NUP82
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MLP1
Gene Ontology Biological Process
- negative regulation of protein import into nucleus during spindle assembly checkpoint [IGI]
- nuclear retention of unspliced pre-mRNA at the site of transcription [IGI, IMP]
- poly(A)+ mRNA export from nucleus [IMP]
- protein import into nucleus [IGI]
- protein localization to nuclear pore [IMP]
- telomere tethering at nuclear periphery [IGI]
- transcriptional activation by promoter-terminator looping [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Maturation Kinetics of a Multiprotein Complex Revealed by Metabolic Labeling.
All proteins interact with other cellular components to fulfill their function. While tremendous progress has been made in the identification of protein complexes, their assembly and dynamics remain difficult to characterize. Here, we present a high-throughput strategy to analyze the native assembly kinetics of protein complexes. We apply our approach to characterize the co-assembly for 320 pairs of nucleoporins (NUPs) ... [more]
Throughput
- High Throughput
Additional Notes
- KARMA
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MLP1 NUP82 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| MLP1 NUP82 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 3384786 | |
| NUP82 MLP1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1451 | BioGRID | 1992439 |
Curated By
- BioGRID