BAIT
DOK
CG2079, Ddok, Dmel\CG2079, l(1)G0331, Dmel_CG2079
Downstream of kinase
GO Process (5)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
SRC42A
CG14471, CG44128, CG7873, DSrc42A, Dm SRC41, DmHD-29, Dmel\CG44128, Dmel_CG14471, Dmel_CG7873, Dsrc41, Dtk5, HD-29, SK2-4, SRC 42A, Src, Src41, Src42, Su(D-raf)1, Su(Raf)1, Su(phl)1, Su1, Tk5, dSrc, dtk-5, l(2)k10108, Dmel_CG44128
Src oncogene at 42A
GO Process (21)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- JNK cascade [TAS]
- actin filament bundle assembly [IMP]
- adherens junction organization [IMP]
- apoptotic cell clearance [IMP]
- axon guidance [IMP]
- cell communication [IDA]
- cell migration [IMP]
- compound eye development [IMP]
- dorsal closure [IGI, IMP, TAS]
- dorsal closure, spreading of leading edge cells [IMP]
- epithelial cell-cell adhesion [IMP]
- imaginal disc fusion, thorax closure [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- negative regulation of epidermal growth factor receptor signaling pathway [IGI]
- negative regulation of synaptic growth at neuromuscular junction [IGI]
- open tracheal system development [IMP]
- peptidyl-tyrosine phosphorylation [IMP]
- protein phosphorylation [IDA, IMP, NAS]
- salivary gland morphogenesis [IMP]
- transmembrane receptor protein tyrosine kinase signaling pathway [IGI]
- tricarboxylic acid cycle [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID