BAIT

SLC6A9

GLYT1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SLC3A2

4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE
solute carrier family 3 (amino acid transporter heavy chain), member 2
Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.

Piniella D, Martinez-Blanco E, Bartolome-Martin D, Sanz-Martos AB, Zafra F

Dopamine (DA) transporters (DATs) are regulated by trafficking and modulatory processes that probably rely on stable and transient interactions with neighboring proteins and lipids. Using proximity-dependent biotin identification (BioID), we found novel potential partners for DAT, including several membrane proteins, such as the transmembrane chaperone 4F2hc, the proteolipid M6a and a potential membrane receptor for progesterone (PGRMC2). We also detected ... [more]

Cell Mol Life Sci Dec. 01, 2021; 78(23);7733-7756 [Pubmed: 34709416]

Throughput

  • Low Throughput

Curated By

  • BioGRID